Author

H. Pope

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2

Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 2 Approach:biophysical modeling· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Approach:experimental assay· 1 Assay:metabolomics· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Tundo· 2 shared A. V. Makela· 2 shared C. H. Contag· 2 shared C. V. Maduka· 2 shared E. Ural· 2 shared M. Alhaj· 2 shared M. M. Kuhnert· 2 shared R. Narayan· 2 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersBioengineering

A. Tundo

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Immunometabolic cues recompose and reprogram the microenvironment around biomaterials

C. V. Maduka, A. D. Schmitter-Sanchez, A. V. Makela, E. Ural, K. B. Stivers, H. Pope, M. M. Kuhnert, O. M. Habeeb, A. Tundo, M. Alhaj, A. Kiselev, S. Chen, A. J. Olive, K. D. D. Hankenson, R. Narayan, , C. H. Contag

The paper shows that immunometabolic cues around biomaterials influence immune cell trafficking and microenvironment composition, promoting a pro-regenerative state through metabolic reprogramming.

bioRxiv · Jul 30, 2023Bioengineering

Polylactide Degradation Activates Immune Cells by Metabolic Reprogramming

C. V. Maduka, M. Alhaj, E. Ural, M. O. Habeeb, M. M. Kuhnert, K. Smith, A. V. Makela, H. Pope, S. Chen, J. M. Hix, C. L. Mallet, S.-J. Chung, M. Hakun, A. Tundo, K. R. Zinn, , C. H. Contag

This study shows that PLA degradation products reprogram cell metabolism, leading to immune activation and inflammation, and demonstrates that targeting metabolism can reduce inflammation and improve biocompatibility.

bioRxiv · Sep 22, 2022Bioengineering