BiophysicsbioRxiv
Sub-3 Angstrom cryo-EM structure of RNA enabled by engineered homomeric self-assembly
D. Liu, F. A. Thelot, J. A. Piccirilli…·P. Yin
This paper introduces a method to improve cryo-EM analysis of RNA structures by engineering kissing-loop sequences for homomeric assembly, achieving high-resolution reconstructions of RNA molecules.
DOI 10.1038/s41592-022-01455-w