Author

H. Sheldon

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Organism:mouse· 1

Frequent Co-Authors

A. L. Harris· 2 shared E. Bridges· 2 shared A. Mcintyre· 1 shared A. Valli· 1 shared B. Kroeger· 1 shared C. Cunningham· 1 shared C. Mendes· 1 shared C. Wilson· 1 shared

Activity by Year

2018-2019 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersCancer Biology

A. L. Harris

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2 papers

Recent·Most cited

Glutamine deprivation regulates the origin and function of cancer cell exosomes

D. Goberdhan, S.-J. Fan, B. Kroeger, P. Marie, E. Bridges, J. Mason, K. McCormick, C. Zois, H. Sheldon, N. Khalid Alham, E. Johnson, M. Elis, I. Stefana, C. Mendes, M. Wainwright, , C. Wilson

This study shows that glutamine deprivation increases exosome release from cancer cells, which promote tumor growth and blood vessel networks through Rab11a-dependent mechanisms.

bioRxiv · Dec 2, 2019Cancer Biology

Hypoxia-induced switch in SNAT2/SLC38A2 regulation generates endocrine-resistance in breast cancer

M. Morotti, E. Bridges, A. Valli, H. Choudhry, H. Sheldon, S. Wigfield, N. Gray, D. Jones, E. J. Teoh, W.-C. Cheng, S. Lord, S. Haider, A. Mcintyre, D. C. I. Goberdhan, F. Buffa, A. L. Harris

This study shows hypoxia shifts SNAT2 regulation from ER to HIF-1 in breast cancer, leading to endocrine resistance and poor outcomes.

bioRxiv · Aug 3, 2018Cancer Biology