Author

F. Kai

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

V. M. Weaver· 3 shared C. Stashko· 2 shared J. J. Northey· 2 shared A. F. Long· 1 shared A. J. Ironside· 1 shared A. M. Leidal· 1 shared A. P. Wiita· 1 shared C. R. Bertozzi· 1 shared

Activity by Year

2017-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersCancer Biology

V. M. Weaver

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Mechanosensitive hormone signaling promotes mammary progenitor expansion and breast cancer progression

J. J. Northey, Y. Yui, M.-K. Hayward, C. Stashko, F. Kai, J. K. Mouw, D. Thakar, J. N. Lakins, A. J. Ironside, S. Samson, R. A. Mukhtar, E. S. Hwang, V. M. Weaver

The paper shows that stiff extracellular matrix and integrin mechanosignaling increase mammary stem-progenitor cells, promoting breast cancer risk and progression through RANK signaling.

bioRxiv · Apr 19, 2022 · PreprintCancer Biology

ECM dimensionality tunes actin tension to modulate the endoplasmic reticulum and spheroid phenotype

F. Kai, G. Ou, R. W. Tourdot, C. Stashko, G. Gaietta, M. F. Swift, N. Volkmann, A. F. Long, Y. Han, H. H. Huang, J. J. Northey, A. M. Leidal, V. Viasnoff, D. M. Bryant, W. Guo, , V. M. Weaver

The paper shows that ECM dimensionality affects actin tension, which in turn modulates endoplasmic reticulum function and spheroid resilience in mammary epithelial cells.

bioRxiv · Jul 14, 2021 · PreprintCell Biology

A Bulky Glycocalyx Fosters Metastasis Formation by Promoting G1 Cell Cycle Progression

E. C. Woods, J. M. Barnes, M. W. Pickup, K. Pedram, F. Kai, M. J. Hollander, V. M. Weaver, C. R. Bertozzi

This study shows that a bulky glycocalyx promotes metastasis by enabling G1 cell cycle progression through integrin adhesion and signaling.

bioRxiv · Jun 28, 2017Cancer Biology