Author

F. Lazure

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 1 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

A. P. Gomes· 2 shared A. Amalric· 1 shared A. Andress Huacachino· 1 shared A. Chatoff· 1 shared A. Hernnandez Corchado· 1 shared A. Jahani-asl· 1 shared A. R. Cole· 1 shared A. Taher Elhaw· 1 shared

Activity by Year

2023-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersImmunology

A. P. Gomes

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Methylmalonic acid induces metabolic abnormalities and exhaustion in CD8+ T cells to suppress anti-tumor immunity

J. Tejero, R. Hesterberg, S. Drapela, D. Ilter, D. Raizada, F. Lazure, H. Kashfi, M. Liu, J. Fernandez-Garcia, S.-M. Fendt, J. Asara, J. Cleveland, A. P. Gomes

This study shows that methylmalonic acid impairs CD8+ T cell function and promotes tumor growth by inducing metabolic dysfunction and exhaustion.

bioRxiv · Mar 3, 2024Immunology

The chemotherapy-induced senescence-associated secretome promotes cell detachment and metastatic dissemination through metabolic reprogramming

A. R. Cole, R. Buj, A. Uboveja, E. Levasseur, H. Wang, K. M. Kedziora, A. Chatoff, A. Andress Huacachino, M. M. Marcinkiewicz, A. Amalric, B. Yang, N. K. Tangudu, J. Danielson, A. Taher Elhaw, S. White, , K. M. Aird

This study shows that chemotherapy-induced senescence-associated secretome promotes metastasis in ovarian cancer by reprogramming metabolism and increasing cell detachment.

bioRxiv · Dec 2, 2023Cancer Biology

The E3 Ubiquitin Ligase Nedd4L Acts as a Checkpoint Against Activation in Quiescent Muscle Stem Cells

D. Blackburn, K. Sahinyan, A. Hernnandez Corchado, F. Lazure, V. Richard, L. Raco, R. Zahedi, C. Borchers, C. Lepper, H. Kawabe, A. Jahani-asl, H. S. Najafabadi, V. D. Soleimani

This study identifies the PAX7/NEDD4L axis as a checkpoint regulating quiescence in muscle stem cells, showing that Nedd4L deletion impairs quiescence and promotes activation.

bioRxiv · May 10, 2023 · PreprintCell Biology