Author

F. Pamula

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 2 Biophysics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Assay:cryo-EM· 2 Research Focus:protein structure prediction· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Organism:human· 1 Assay:structural biology· 1 Research Focus:synaptic & neural circuits· 1

Frequent Co-Authors

C.-J. Tsai· 3 shared X. Deupi· 3 shared H. Stahlberg· 2 shared R. Guixa-Gonzalez· 2 shared A. D. Diethelm· 1 shared A. Furrer· 1 shared A. Grahl· 1 shared A. Wach· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersBiochemistry

C.-J. Tsai

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

ULTRAFAST STRUCTURAL CHANGES DIRECT THE FIRST MOLECULAR EVENTS OF VISION

T. Gruhl, T. Weinert, M. Rodrigues, C. J. Milne, G. Ortolani, K. Nass, E. Nango, S. Sen, P. J. Johnson, C. Cirelli, A. Furrer, S. Mous, P. Skopintsev, D. James, F. Dworkowski, , Scher

This study uses ultrafast crystallography to reveal how photoactivated retinal initiates structural changes in rhodopsin, leading to GPCR activation and vision.

bioRxiv · Oct 14, 2022 · PreprintBiochemistry

Structural basis of the activation of the CC chemokine receptor 5 by a chemokine agonist

P. Isaikina, C.-J. Tsai, N. B. Dietz, F. Pamula, A. Grahl, K. N. Goldie, R. Guixa-Gonzalez, G. F. X. Schertler, O. Hartley, H. Stahlberg, T. Maier, X. Deupi, S. Grzesiek

The paper reports the cryo-EM structure of CCR5 bound to a chemokine agonist and Gi protein, revealing its activation mechanism.

bioRxiv · Nov 27, 2020Biophysics

Cryo-EM structure of the rhodopsin-Gαi-βγ complex reveals binding of the rhodopsin C-terminal tail to the Gβ subunit

C.-J. Tsai, J. Marino, R. J. Adaixo, F. Pamula, J. Muehle, S. Maeda, T. Flock, N. M. Taylor, I. Mohammed, H. Matile, R. J. Dawson, X. Deupi, H. Stahlberg, G. F. Schertler

The paper presents a cryo-EM structure of the rhodopsin-Gαi-βγ complex, revealing the C-terminal tail of rhodopsin bound to the Gβ subunit and identifying common anchoring points across G protein-subtype interactions.

bioRxiv · Feb 12, 2019Biochemistry