Author

F. Sumbul

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Approach:biophysical modeling· 1 Organism:chicken / avian· 1 Organism:human· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

A. J. Crawford· 1 shared A. Meola· 1 shared A. Sharma· 1 shared C. Gosse· 1 shared C. Valotteau· 1 shared D. Kostrz· 1 shared E. Baquero· 1 shared F. A. Rey· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperEvolutionary Biology

A. J. Crawford

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2 papers

Recent·Most cited

Modulation of SARS-CoV-2 spike binding to ACE2 throughconformational selection

P. Saha, I. Fernanadez, F. Sumbul, C. Valotteau, D. Kostrz, A. Meola, E. Baquero, A. Sharma, J. R. Portman, F. Stransky, T. Boudier, P. Guardado Calvo, C. Gosse, T. Strick, F. A. Rey, F. Rico

This study uses single-molecule techniques to show that SARS-CoV-2 spike protein RBD dynamics modulate ACE2 binding through conformational selection without affecting unbinding.

bioRxiv · Mar 15, 2024Biophysics

Epistatic effects between amino acid insertions and substitutions mediate toxin-resistance of vertebrate Na+,K+-ATPases

S. Mohammadi, H. I. Özdemir, P. Ozbek, F. Sumbul, J. Stiller, Y. Deng, A. J. Crawford, H. M. Rowland, J. F. Storz, P. Andolfatto, S. Dobler

The paper shows how amino acid insertions and substitutions in Na+,K+-ATPase affect toxin resistance in different vertebrate lineages through epistatic interactions.

bioRxiv · Sep 1, 2022Evolutionary Biology