Author

F. Vondran

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 1 Molecular Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Organism:human· 3 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

A. Pfeiffer· 1 shared B. M. Reinecke· 1 shared B. Qu· 1 shared C. Miskey· 1 shared D. Bojkova· 1 shared D. Todt· 1 shared E. Steinmann· 1 shared F. Rothweiler· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperPharmacology & Toxicology

A. Pfeiffer

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Hepatitis C virus cell culture adaptive mutations enhance cell culture propagation by multiple mechanisms but boost antiviral responses in primary human hepatocytes

N. Frericks, R. J. P. Brown, B. M. Reinecke, M. Herrmann, Y. Brueggemann, D. Todt, C. Miskey, F. Vondran, E. Steinmann, T. Pietschmann, J. A. Sheldon

This study identifies cell culture adaptive mutations in HCV that enhance replicative fitness in cell lines but reduce virion production in primary human hepatocytes by boosting antiviral responses.

bioRxiv · Nov 22, 2023 · PreprintMolecular Biology

Identification of novel antiviral drug candidates using an optimized SARS-CoV-2 phenotypic screening platform

D. Bojkova, P. Reus, L. Panosch, M. Bechtel, T. Rothenburger, J. Kandler, A. Pfeiffer, J. U. Wagner, M. Shumliakivska, S. Dimmeler, R. Olmer, U. Martin, F. Vondran, T. Toptan, F. Rothweiler, , J. Cinatl

This study develops a phenotypic screening platform using caspase 3/7 activity to identify antiviral compounds against SARS-CoV-2, including novel candidates and combinations.

bioRxiv · Jul 17, 2022Pharmacology & Toxicology

HBV DNA is a substrate for the cGAS/STING pathway but is not sensed in infected hepatocytes

L. Lauterbach-Riviere, M. Bergez, S. Mönch, B. Qu, M. Riess, F. Vondran, J. Liese, V. Hornung, S. Urban, R. Koenig

This study shows HBV DNA is sensed by cGAS/STING in hepatocytes but is not detected during infection due to capsid shielding, while HBV RNAs are not immunostimulatory.

bioRxiv · Dec 6, 2019Microbiology