M. Arnoldini

Quantifying the varying harvest of fermentation products from the human gut microbiota

The paper quantifies the metabolic flux of fermentation products from the gut microbiota, showing it varies with diet but not microbiota composition.

The differing prevalences of propionate and butyrate producing bacteria in the human gut microbiota

The paper analyzes the prevalence of propionate and butyrate producing pathways in the human gut microbiota across different age groups and birth methods, finding significant variations linked to host physiology.

Nanoscale clustering by O-antigen-Secretory Immunoglobulin-A binding limits outer membrane diffusion by encaging individual Salmonella cells

The paper shows SIgA binding to Salmonella O-antigen nanoscale crosslinks the outer membrane, leading to biased inheritance and accelerated IgA escape through phase-variation.

Targeted induction of gut-microbial metabolism acutely affects feeding patterns and clock gene expression in the host

This study shows that increasing gut microbial metabolism in mice affects host clock gene expression and reduces food intake beyond microbial calorie contribution.

Fitness advantage of Bacteroides thetaiotaomicron capsular polysaccharide is dependent on the resident microbiota

This study quantifies colonization bottlenecks and growth dynamics of Bacteroides thetaiotaomicron in the gut, showing that capsular polysaccharide provides a fitness advantage dependent on microbiota composition.

Metabolic reconstitution by a gnotobiotic microbiota varies over the circadian cycle

This study shows that a gnotobiotic microbiota affects metabolic processes differently depending on the circadian cycle, influencing energy balance and substrate utilization.

A rationally designed oral vaccine induces Immunoglobulin A in the murine gut that directs the evolution of attenuated Salmonella variants

This paper shows that an oral vaccine inducing IgA in mice can direct Salmonella to evolve into less virulent variants with shorter O-antigens.