Author

S. Khadayate

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1 Immunology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 4 Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:cell signaling & trafficking· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

D. J. Withers· 2 shared A. Barr· 1 shared A. I. Choudhury· 1 shared A. Marta· 1 shared A. Montoya· 1 shared A. Osakwe· 1 shared A.-M. Moody· 1 shared B. Patel· 1 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersPhysiology

D. J. Withers

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Ribosomal S6 kinase 1 regulates inflammaging via the senescence secretome

S. Gallage, E. E. Irvine, S. Pedroni, J. E. Barragan Avila, S. Khadayate, J. Pombo, S. Brookes, D. Heide, G. Dharmalingam, A. I. Choudhury, N. Herranz, S. Vernia, M. Heikenwalder, J. Gil, D. J. Withers

This study shows that S6K1 deletion reduces inflammation and immune infiltration in aged livers, suggesting it suppresses the inflammatory SASP, contributing to healthspan benefits.

bioRxiv · Oct 17, 2023Physiology

Metabolomic and transcriptomic analyses of Fmo5-/- mice reveal roles for flavin-containing monooxygenase 5 (FMO5) in NRF2-mediated oxidative stress, the unfolded protein response, lipid homeostasis, and carbohydrate and one-carbon metabolism

I. Phillips, S. Veeravalli, S. Khadayate, E. Shephard

This study uses metabolomic and transcriptomic analyses of Fmo5-/- mice to identify FMO5's roles in oxidative stress, lipid homeostasis, and metabolic pathways.

bioRxiv · Feb 9, 2023 · PreprintBiochemistry

Differential CpG methylation at Nnat in the early establishment of beta cell heterogeneity

V. Yu, F. Yong, A. Marta, S. Khadayate, A. Osakwe, S. Bhattacharya, S. S. Varghese, P. Chabosseau, S. M. Tabibi, K. Chen, E. Georgiadou, N. Parveen, M. Suleiman, Z. Stamoulis, L. Marselli, , S. J. Millership

This study identifies differential CpG methylation at the Nnat gene as a mechanism establishing beta cell heterogeneity during development and its potential role in diabetes.

bioRxiv · Feb 4, 2023Cell Biology

RUNX1 controls the dynamics of cell cycle entry of naive resting B cells by regulating expression of cell cycle and immunomodulatory genes in response to BCR stimulation

I. Thomsen, N. Kunowska, R. de Souza, A.-M. Moody, G. Crawford, Y.-F. Wang, S. Khadayate, J. Strid, M. M. Karimi, A. Barr, N. Dillon, P. Sabbattini

This study shows RUNX1 regulates B cell cycle entry and immunomodulatory gene expression in response to BCR stimulation, linking it to autoimmunity.

bioRxiv · Dec 1, 2020Immunology