G. J. Graham

This study shows that combining CXCR2 inhibition with anti-PD1 therapy enhances immunotherapy response in NASH-HCC by reprogramming tumor-associated neutrophils.

This study generates multi-chemokine receptor reporter mice to analyze receptor expression dynamics on myeloid cells, revealing high specificity and selectivity in chemokine receptor expression.

This study identifies Ly6G expression levels as a marker for neutrophil maturation stages and shows spleen-derived neutrophils mature faster with distinct transcriptional profiles.

The paper identifies diverse myeloid cell recruitment in developing and inflamed mammary glands and shows inflammation alters terminal end bud abundance during puberty.

This study shows that selecting dendritic cells with high CCR7 expression improves their ability to migrate to lymph nodes and enhance anti-tumour immune responses in melanoma models.

The paper shows that activating innate immune responses at the mosquito bite site, specifically targeting skin-resident macrophages, can inhibit systemic arbovirus dissemination and improve clinical outcomes.

This study shows that CXCR2 deficiency in mice leads to reduced subcutaneous adipose tissue due to smaller adipocytes, primarily in females.