In vivo CRISPR screens reveal SCAF1 and USP15 as novel drivers of pancreatic cancer
S. Martinez, R. Weber, T. Woo, A. Malik, M. Geuenich, G. H. Jang, D. Dervovic, K. Al-Zahrani, R. Tsai, N. Fodil, P. Gros, S. S. Sidhu, S. Gallinger, G. Neely, K. Campbell, , D. Schramek
This study uses in vivo CRISPR screens to identify USP15 and SCAF1 as novel tumor suppressors in pancreatic cancer, with potential therapeutic implications.
bioRxiv · Mar 13, 2022Cancer Biology