Sympathetic neuron-derived NPY protects from obesity by sustaining the mural progenitors of thermogenic adipocytes.
Y. Zhu, L. Yao, A. L. Gallo-Ferraz, B. Bombassaro, M. R. Simoes, I. Abe, J. Chen, G. Sarker, A. Ciccarelli, C. Lee, N. Martinez-Sanchez, M. Dustin, K. Anderson, C. Zhan, T. Horvath, , A. I. Domingos
This study shows that sympathetic neuron-derived NPY sustains mural progenitors of thermogenic adipocytes, protecting against obesity by maintaining thermogenic capacity.
bioRxiv · May 18, 2024 · PreprintPhysiology