P. Chaturvedi

This study shows that PERK inhibition reduces SLC7A11 expression and sensitizes colon cancer cells to ferroptosis, suggesting PERK inhibitors as potential therapeutics.

This study evaluates crofelemer's effectiveness in reducing neratinib-induced diarrhea in female dogs, showing a 30% reduction in incidence and severity without loperamide.

The paper uses proximity labelling to identify novel components in chloroplast development in Arabidopsis seedlings.

This study shows that Src and Hif1α activation increases glycolytic ATP production near endothelial adherens junctions, facilitating their re-assembly after injury.

This study shows that cytotoxic chemotherapy in TNBC increases BCSCs via HIFs, leading to relapse, and that HIF inhibitors can block this effect.

The paper uses molecular dynamics simulations to reveal how sulfonated nanoparticles disrupt HPV16 capsid protein interfaces, leading to virucidal activity.

This study evaluates the antifungal activity of Conocephalum conicum extracts against Fusarium oxysporum f. sp. lycopersici, finding significant inhibition and suggesting its potential as an eco-friendly biocontrol agent.

This study shows salinomycin inhibits EZH2 in colon CSCs, enhancing DR4/DR5 expression and reducing CSC traits, suggesting a therapeutic strategy combining TRAIL and EZH2 inhibitors.

The paper shows that intracellular CXCR4 protein, not its signaling, promotes drug resistance and tumorigenicity by downregulating DR5 through transcription factor modulation.

This paper extends the BAC TG-EMBED method to enable versatile, stable, and reproducible multi-transgene expression in mammalian cells using episomal and integrated BAC constructs.