Author

C. Soto

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 4 Microbiology· 2 Bioengineering· 1 Cell Biology· 1 Ecology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 7 Organism:human· 5 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2

Frequent Co-Authors

J. E. Crowe· 2 shared P. Gilchuk· 2 shared R. H. Carnahan· 2 shared R. S. Nargi· 2 shared A. Alape-Giron· 1 shared A. B. Ward· 1 shared A. Dev· 1 shared A. Diaz-Pulido· 1 shared

Activity by Year

2019-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 11 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersImmunology

J. E. Crowe

Mutual co-authors in cluster

Author profile →

9 papers

Recent·Most cited

Development of a Nanoparticle-Based Tendon-Targeting Drug Delivery System to Pharmacologically Modulate Tendon Healing

E. E. Adjei-Sowah, I. Chandrasiri, B. Xiao, Y. Liu, J. Ackerman, C. Soto, A. E. Nichols, K. Nolan, D. S. W. Benoit, A. E. Loiselle

This paper develops a nanoparticle-based drug delivery system targeting tendons to improve healing by delivering Niclosamide, showing enhanced functional and mechanical outcomes compared to systemic delivery.

bioRxiv · Nov 29, 2023Bioengineering

Mesenchymal stem cells ameliorate inflammation in an experimental model of Crohn's disease via the mesentery

M. Dave, A. Dev, R. A. Somoza, N. Zhao, S. Viswanath, P. R. Mina, P. Chirra, V. C. Obmann, G. H. Mahabeleshwar, P. Menghini, B. D. Johnson, J. A. Nolta, C. Soto, A. Osme, L. T. Khuat, , F. Cominelli

This study shows that mesenchymal stem cells (MSCs) reduce inflammation in a mouse model of Crohn's disease by modulating T cells and macrophages in the mesentery, with long-term effects through macrophage reprogramming.

bioRxiv · May 22, 2023 · PreprintImmunology

Forest cover is more important than habitat integrity or landscape configuration in determining habitat use by mammals in a human-modified landscape in Colombia

L. E. Pardo, B. Gomez-Valencia, N. Deere, Y. Herrera Varon, C. Soto, E. A. Noguera-Urbano, L. M. Sanchez-Clavijo, L. Romero, A. Diaz-Pulido, J. M. Ochoa-Quintero

The paper assesses the impact of land-use changes on mammalian habitat use in Colombia, finding that forest cover is more important than habitat integrity or landscape configuration.

bioRxiv · Feb 27, 2023 · PreprintEcology

Aβ oligomers trigger necroptosis-mediated neurodegeneration via microglia activation in Alzheimer's disease.

N. Salvadores, I. Moreno, N. Gamez, G. Quiroz, L. Vegas, M. Escandon, S. Jimenez, J. Vitorica, A. Gutierrez, C. Soto, F. Court

This study shows Aβ oligomers induce necroptosis in neurons via microglia activation, leading to neurodegeneration in Alzheimer's disease, and suggests necroptosis inhibition as a potential therapeutic target.

bioRxiv · Aug 27, 2021Cell Biology

High efficacy of therapeutic equine hyperimmune antibodies against SARS CoV-2 variants of concern

A. Moreira-Soto, M. Arguedas, H. Brenes, W. Bujan, E. Corrales-Aguilar, C. Diaz, A. Echeverri, M. Flores-Diaz, A. Gomez, A. Hernandez, M. Herrera, G. Leon, R. Macaya, A. Khüne, J. A. Molina-Mora, , J. F. Drexler

This study demonstrates that therapeutic equine polyclonal antibodies effectively neutralize SARS-CoV-2 variants of concern.

bioRxiv · Jun 12, 2021 · PreprintMicrobiology

Commercial vaccines do not confer protection against two genetic strains of Piscirickettsia salmonis, LF-89-like and EM-90-like, in Atlantic salmon.

C. Figueroa, D. Torrealba, B. Morales-Lange, L. Mercado, B. Dixon, P. Conejeros, G. Silva, C. Soto, J. A. Gallardo

This study evaluates the efficacy of a commercial vaccine against two Piscirickettsia salmonis strains in Atlantic salmon, finding no significant survival differences between vaccinated and unvaccinated fish.

bioRxiv · Jan 7, 2021 · PreprintImmunology

Canonical features of human antibodies recognizing the influenza hemagglutinin trimer interface

S. J. Zost, J. Dong, I. M. Gilchuk, P. Gilchuk, N. J. Thornburg, S. Bangaru, N. Kose, J. A. Finn, R. Bombardi, C. Soto, R. S. Nargi, R. P. Irving, N. Suryadevara, J. B. Westover, R. H. Carnahan, , J. E. Crowe

The paper identifies common genetic and structural features of human antibodies recognizing the influenza HA trimer interface, suggesting it as a target for vaccine design.

bioRxiv · Dec 31, 2020Immunology

Integrated technology platform for accelerated discovery of antiviral antibody therapeutics

P. Gilchuk, R. G. Bombardi, J. H. Erasmus, Q. Tan, R. S. Nargi, C. Soto, P. Abbink, T. J. Suscovich, L. A. Dunellin, A. Khandhar, J. Archer, J. Liang, M. E. Fouch, E. Davidson, B. Doranz, , R. H. Carnahan

This study develops an integrated platform to rapidly discover and validate potent antiviral human monoclonal antibodies against Zika virus.

bioRxiv · May 12, 2020Immunology

Bacterial DNA promotes Tau aggregation

G. Tetz, M. Pinho, C. Soto, S. Pritzkow, N. Mendez, V. Tetz

This study shows bacterial DNA promotes tau misfolding and aggregation more than eukaryotic DNA, suggesting microbial DNA may contribute to Alzheimer's disease pathogenesis.

bioRxiv · Sep 30, 2019Microbiology