ImmunologybioRxiv
Dynamic control of gene expression by ISGF3 and IRF1 duringIFNbeta and IFNgamma signaling
A. Ravi Sundar Jose Geetha, K. Fischer, G. Smesnik…·T. Decker
The paper shows that IFN-I and IFN-gamma produce distinct transcriptomes over time due to different roles of ISGF3 and IRF1 in enhancer activation and chromatin accessibility.
DOI 10.1038/s44318-024-00092-7