Oral Lisinopril Raises Tissue Levels of ACE2, the SARS-CoV-2 Receptor, in Healthy Male and Female Mice
S. D. Brooks, R. L. Smith, A. d. S. Moreira, H. Ackerman
This study shows oral lisinopril increases ACE2 levels in multiple tissues of mice, while combining it with losartan prevents this increase and reduces Ace2 gene expression.
bioRxiv · Oct 19, 2021Pharmacology & Toxicology