Niclosamide potentiates TMEM16A and induces vasoconstriction
P. Liang, Y. C. S. Wan, K. Yu…·H. Yang
This study shows niclosamide potentiates TMEM16A and induces vasoconstriction, challenging its use as a TMEM16A inhibitor for asthma and COPD.
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4 papers
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P. Liang, Y. C. S. Wan, K. Yu…·H. Yang
This study shows niclosamide potentiates TMEM16A and induces vasoconstriction, challenging its use as a TMEM16A inhibitor for asthma and COPD.
S. J. Foltz, Y. Y. Cui, H. J. Choo, H. C. Hartzell
This study shows that ANO5 deficiency disrupts annexin trafficking to the injury site in muscle fibers, leading to impaired membrane repair and prolonged calcium elevation.
K. Yu, T. Jiang, Y. Cui…·H. C. Hartzell
This study identifies three PI(4,5)P2 binding sites on ANO1 that allosterically regulate its Ca2+-activated Cl- channel gating through molecular dynamics and electrophysiology.
L. Encarnacion-Rivera, S. Foltz, H. C. Hartzell, H. Choo
Myosoft automates muscle histology analysis using machine learning in FIJI/ImageJ, providing faster and more accurate results than manual methods.