Author

S. Devos

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3 Microbiology· 3 Bioengineering· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Assay:proteomics· 4 Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Organism:human· 3 Research Focus:drug response / drug discovery· 2 Research Focus:host-pathogen & immune response· 2 Assay:protein sequence· 2

Frequent Co-Authors

F. Impens· 3 shared H. Demol· 3 shared N. Callewaert· 3 shared T. M. Maia· 3 shared W. Nerinckx· 3 shared A. Staes· 2 shared B. Schepens· 2 shared C. Lonigro· 2 shared

Activity by Year

2020-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersBiochemistry

F. Impens

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

A multi-year longitudinal harmonization of quality controls in mass spectrometry proteomics core facilities

C. Chiva, R. Olivella, A. Staes, T. M. Maia, C. Panse, K. Stejskal, T. Douche, B. Lombard, A. Schuhmann, D. Loew, K. Mechtler, M. Matondo, M. Rettel, D. Helm, F. Impens, , E. Sabido

This study harmonizes quality controls across proteomics core facilities to improve data comparability and reliability through a 4-year longitudinal dataset and common processing software.

bioRxiv · May 19, 2024 · PreprintBiochemistry

Yeast-based production platform for potent and stable heavy chain-only antibodies

C. Lonigro, H. Eeckhaut, R. A. Symakani, K. Roose, B. Schepens, K. Sedeyn, A.-S. De Smet, J. C. Zavala Marchan, P. Vanhaverbeke, S. Vanmarcke, K. Claes, S. De Cae, H. Demol, S. Devos, D. Fijalkowska, , N. Callewaert

This paper presents a yeast-based platform for producing stable and potent heavy chain-only antibodies, demonstrating its effectiveness with an anti-SARS-CoV-2 example.

bioRxiv · Mar 4, 2024 · PreprintMicrobiology

High-throughput nano-flow proteomics using a dual-column electrospray source

A. Staes, K. Boucher, S. Dufour, T. M. Maia, E. Timmerman, D. Van Haver, J. Pauwels, H. Demol, J. Vandenbussche, F. Impens, S. Devos

The paper introduces a dual-column electrospray source for nano-flow proteomics to improve throughput while maintaining sensitivity in low-input samples.

bioRxiv · Feb 13, 2024 · PreprintBiochemistry

Integrating multiple omics levels using the human protein complexome as a framework, a multi-omics study of inborn errors of metabolism

M. Guharoy, I. Adant, M. Bird, A. J. Pedrayes, A. Botzki, J. Dehairs, S. Derveaux, S. Devos, G. Goeminne, F. Impens, R. Janky, R. Maes, T. M. Maia, W. Meersseman, D. Rymen, , B. Ghesquiere

This study integrates proteomics, transcriptomics, and metabolomics data from IEM patients to identify perturbed protein complexes and pathways, highlighting mitochondrial oxidative phosphorylation and histone acetylation dysregulation.

bioRxiv · Dec 30, 2023 · PreprintBiochemistry

Barley cultivars shape the abundance, phenotype, genotype and gene expression of their associated microbiota by differential root exudate secretion

A. Pacheco-Moreno, A. Bollmann-Giolai, G. Chandra, P. Brett, J. Davies, O. Thornton, P. Poole, V. Ramachandran, J. Brown, P. Nicholson, C. Ridout, S. DeVos, J. G. Malone

bioRxiv · Jul 5, 2023 · PreprintMicrobiology

Ultrapotent SARS coronavirus-neutralizing single-domain antibodies that bind a conserved membrane proximal epitope of the spike

S. De Cae, I. Van Molle, L. van Schie, S. R. Shoemaker, J. Deckers, N. Debeuf, S. Lameire, W. Nerinckx, K. Roose, D. Fijalkowska, S. Devos, A.-S. Desmet, J. C. Zavala Marchan, T. Venneman, G. H. Ghassabeh, , B. Schepens

The paper identifies ultrapotent SARS-CoV-2-neutralizing nanobodies that bind a conserved epitope on the spike protein, showing therapeutic efficacy in hamsters.

bioRxiv · Mar 10, 2023 · PreprintMicrobiology

GlyConnect: a glycan-based conjugation extension of the GlycoDelete technology

W. Van Breedam, K. Thooft, F. Santens, S. Vanmarcke, E. Wyseure, B. Laukens, B. Van Moer, W. Nerinckx, S. Devos, A. Madder, N. Callewaert

The paper evaluates and optimizes chemical and chemo-enzymatic conjugation methods for GlycoDelete-type glycans on benchmark proteins.

bioRxiv · Jun 2, 2021 · PreprintBioengineering

Amplification, not spreading limits rate of tau aggregate accumulation in Alzheimer's disease

G. Meisl, Y. Zuo, K. Allinson, T. Rittman, S. DeVos, J. S. Sanchez, C. K. Xu, K. E. Duff, K. A. Johnson, J. Rowe, B. Hyman, T. P. Knowles, D. Klenerman

The paper quantifies tau aggregate replication rates in Alzheimer's disease and finds local replication, not spreading, limits tau accumulation in neocortical regions.

bioRxiv · Nov 16, 2020 · PreprintBiophysics