Cancer BiologybioRxivPreprint
Germline determinants of the prostate tumor genome
K. E. Houlahan, J. Yuan, T. Schwarz…·P. C. Boutros
The paper identifies germline-determined quantitative trait loci (dQTLs) that influence somatic mutational features in prostate cancer, revealing their impact on tumor epigenome, transcriptome, and proteome.
DOI 10.1101/2022.11.16.516773