Author

J. L. Gommerman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

V. Ramaglia· 2 shared A. A. Bianchi· 1 shared A. J. McGeer· 1 shared A. Martin· 1 shared A. Nguyen· 1 shared A. P. Dupuis· 1 shared A. Pu· 1 shared A. Sharma· 1 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 11 mutual co-author links

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2 shared papersImmunology

V. Ramaglia

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Age related susceptibility to grey matter demyelination and neurodegeneration is associated with meningeal neutrophil accumulation in an animal model of Multiple Sclerosis

M. Zuo, N. Fettig, L.-P. Bernier, E. Possnecker, S. Spring, A. Pu, X. I. Ma, D. S. Lee, L. Ward, A. Sharma, J. Kuhle, J. G. Sled, A.-K. Probstel, B. A. MacVicar, L. C. Osborne, , V. Ramaglia

The paper shows that age-related grey matter demyelination and neurodegeneration in MS are linked to meningeal neutrophil accumulation in an animal model.

bioRxiv · Dec 23, 2021 · PreprintImmunology

A simple protein-based surrogate neutralization assay for SARS-CoV-2

K. T. Abe, Z. Li, R. Samson, P. Samavarchi-Tehrani, E. J. Valcourt, H. Wood, P. Budylowski, A. P. Dupuis, R. C. Girardin, B. Rathod, K. Colwill, A. J. McGeer, S. Mubareka, J. L. Gommerman, Y. Durocher, , A.-C. Gingras

The paper introduces a protein-based assay to detect neutralizing antibodies against SARS-CoV-2, showing it correlates with traditional viral neutralization tests.

bioRxiv · Jul 10, 2020Immunology

The eIF2α kinase HRI triggers the autophagic clearance of cytosolic protein aggregates

M. Abdel-Nour, V. Ramaglia, A. A. Bianchi, J. Tsalikis, H. N. Chau, S. K. Kalia, L. V. Kalia, J.-J. Chen, D. Arnoult, J. L. Gommerman, D. J. Philpott, S. E. Girardin

This study shows that HRI enhances autophagic clearance of cytosolic protein aggregates when the UPS is inhibited, and its absence leads to aggregate accumulation and cytotoxicity in both cell and mouse models.

bioRxiv · May 12, 2020Cell Biology

Perinatal Programming of Mucosal Stromal Cell Identity by the Lymphotoxin Pathway Regulates Mucosal Immune Responses in the Adult

C. Li, E. Lam, C. Perez-Shibayama, D. Lee, L. A. Ward, A. Nguyen, M. Ahmed, K. V. Korneev, O. Rojas, T. Sun, H. H. He, A. Martin, B. Ludewig, J. L. Gommerman

This study shows that in utero Lymphotoxin-beta receptor signaling programs mesenteric lymph node stromal cells to support adult IgA responses by influencing antibody class switch and IgA+ cell generation.

bioRxiv · Feb 21, 2019Immunology