PhysiologybioRxiv
Salt-inducible kinase inhibition promotes the adipocyte thermogenic program and adipose tissue browning
F. Shi, F. de Fatima Silva, D. Liu…·S. Collins
This study identifies SIK3 as a key mediator of β-adrenergic signaling in adipose thermogenesis, showing that its inhibition promotes browning and thermogenic gene expression.
DOI 10.1016/j.molmet.2023.101753