I. Adameyko

This study develops a theoretical framework to analyze how global and local cues influence branching morphogenesis, using zebrafish innervation as a model system.

The paper identifies an immature neuroblastoma subset that synthesizes retinoic acid and is resistant to it, potentially contributing to therapy-resistant relapses.

The paper identifies distinct cellular identities in low and high-risk neuroblastoma tumors using single-nuclei transcriptomes, linking them to clinical outcomes and age at diagnosis.

This study identifies the secondary ossification center's role in protecting growth plate hypertrophic chondrocytes from mechanical stress during terrestrial adaptation.

The paper identifies a subpopulation of malignant Schwann cell precursor-like cells in neuroblastoma that connects adrenergic and mesenchymal tumor cells, suggesting intratumoral plasticity mechanisms.

The paper identifies error-prone bypass of DNA lesions on the lagging strand as a major source of human germline and cancer mutations, supported by mutational asymmetry analysis and experimental validation.