Author

I. Clark

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cell Biology· 3 Cancer Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Organism:fungi (other)· 3 Research Focus:cell signaling & trafficking· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. A. Jeyaprakash· 2 shared C. Spanos· 2 shared I. Leontiou· 2 shared K. Aktar· 2 shared K. G. Hardwick· 2 shared T. Davies· 2 shared A. Abate· 1 shared A. C. Logan· 1 shared

Activity by Year

2022-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCell Biology

A. A. Jeyaprakash

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

The dependence of shugoshin on Bub1-kinase activity is dispensable for the maintenance of spindle assembly checkpoint response in Cryptococcus neoformans

S. D. Polisetty, K. Bhat, K. Das, I. Clark, K. G. Hardwick, K. Sanyal

This study shows that Sgo1 maintains SAC signals in Cryptococcus neoformans by regulating Aurora B kinase and PP1 levels at kinetochores, independent of Bub1 kinase activity.

bioRxiv · Feb 28, 2024 · PreprintCell Biology

Multiomic Single Cell Sequencing Identifies Stemlike Nature of Mixed Phenotype Acute Leukemia and Provides Novel Risk Stratification

C. A. C. Peretz, V. E. Kennedy, A. Walia, C. L. Delley, A. Koh, E. Tran, I. Clark, C. E. Hayford, C. D'Amato, Y. Xue, K. M. Fontanez, R. Roy, A. C. Logan, A. E. Perl, A. Abate, , C. C. Smith

The paper uses multiomic single-cell profiling to show MPAL blasts have a stem-like transcriptional profile linked to poor prognosis and develops a gene score for clinical risk stratification.

bioRxiv · May 15, 2023 · PreprintCancer Biology

mps1 and mad mutations reduce Cryptococcus neoformans titan cell viability

K. Aktar, T. Davies, I. Leontiou, I. Clark, C. Spanos, E. Wallace, L. Tuck, A. A. Jeyaprakash, K. Hardwick

This study shows that mutations in mps1 and mad genes reduce viability of Cryptococcus neoformans titan cells during reductive division.

bioRxiv · Apr 9, 2023 · PreprintCell Biology

Bub1 kinase acts as a signalling hub for the entire Cryptococcus neoformans spindle assembly checkpoint pathway

I. Leontiou, T. Davies, I. Clark, K. Aktar, A. P. Suresh, M. A. Abad, C. Spanos, K.-T. Lee, Y.-S. Bahn, A. A. Jeyaprakash, K. G. Hardwick

This study identifies CnBub1 as a multifunctional protein in Cryptococcus neoformans that integrates both Bub1 and Mad3/BubR1 functions in the spindle assembly checkpoint.

bioRxiv · Sep 21, 2022 · PreprintCell Biology