A. A. Jeyaprakash

The paper shows that DHRS7 loss increases nuclear size in prostate cancer cells and that estradiol propionate reduces nuclear size in DHRS7-lacking cells, suggesting DHRS7 as a biomarker for estrogen therapy effectiveness.

The paper identifies a novel histone H4 variant in Oryza that modulates salt stress responses through chromatin remodeling and acetylation marks.

The paper shows that Mis18 directly binds to SPB components to recruit Mis18C, promoting CENP-A chromatin assembly independently of centromeres.

This study shows that mutations in mps1 and mad genes reduce viability of Cryptococcus neoformans titan cells during reductive division.

This study identifies CnBub1 as a multifunctional protein in Cryptococcus neoformans that integrates both Bub1 and Mad3/BubR1 functions in the spindle assembly checkpoint.

This study characterizes the structure of the Mis18 complex and identifies structural determinants essential for its assembly and centromere maintenance.

This study identifies the molecular mechanism of CPC-Sgo1 interaction and shows its role in centromere localization and function through structural and functional analyses.

This study identifies a conserved binding pocket on PP2A-B56 essential for Sgo1 interaction and cohesion protection, showing that complex formation is not strictly required for cohesion protection.

This study identifies SUMOylation as a mechanism that stabilizes sister kinetochore biorientation by modulating Aurora B kinase and PP2A interactions.

This study investigates the interaction between NDC80 and Ska complexes at the kinetochore-microtubule interface, showing that Hec1 tail phosphorylation affects attachment stability independently of Ska and mapping Ska's location relative to NDC80.

This study reveals how Drosophila CAL1 targets CENP-A to centromeres via structural interactions with CENP-A/H4 and CENP-C, bypassing the need for the Mis18 complex.

This study identifies Borealin as the key mediator of Chromosomal Passenger Complex (CPC) chromosome association through direct nucleosome binding, revealing its critical role in chromosome segregation.