I. Kaverina

This study shows that glucose stimulates KIF5B-mediated microtubule sliding in pancreatic beta cells, organizing microtubule networks to support insulin secretion and prevent hypoglycemia.

This study shows CLASP2 crosslinks F-actin to microtubules, promoting actin filament organization along microtubule lattices and affecting cytoskeletal structure.

This study shows that CAMSAP2 in primary pancreatic β-cells localizes to the Golgi and supports insulin secretion by facilitating Golgi-ER trafficking, despite not regulating microtubule dynamics.

The paper identifies VSF merging as a mechanism for aligning long contractile fibers in fibroblasts, driven by mechanical forces and adhesion dynamics.

This paper introduces FAFCK, a tool for automated analysis of focal adhesions and actin stress fibers, enabling correlation studies to improve mechanocellular force analysis.

The paper investigates how microtubules and Gαo-signaling regulate the preferential secretion of newly synthesized insulin granules in β cells, showing that their absence leads to increased secretion of older granules.

This study shows microtubules regulate beta cell heterogeneity in insulin secretion by controlling secretion hot spots through spatiotemporal dynamics.

This study shows microtubules regulate insulin granule localization and PM interactions in beta cells, affecting GSIS and suggesting MT targeting as a diabetes therapy.

This study identifies how PTPN21 relieves KIF1C autoinhibition, enabling cargo-specific transport and bidirectional movement.