Author

M. Zanic

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cell Biology· 6 Biophysics· 3

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell signaling & trafficking· 9 Approach:experimental assay· 8 Research Focus:cell type annotation· 4 Organism:human· 3 Assay:imaging· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

E. J. Lawrence· 3 shared G. Arpag· 3 shared C. Arnaiz· 2 shared I. Kaverina· 2 shared M. K. Gardner· 2 shared A. B. Osipovich· 1 shared A. J. Mauro· 1 shared A. L. Erwin· 1 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersCell Biology

E. J. Lawrence

Mutual co-authors in cluster

Author profile →

9 papers

Recent·Most cited

CLASPs stabilize the intermediate state between microtubule growth and catastrophe

E. J. Lawrence, S. Chatterjee, M. Zanic

This study shows CLASP1 stabilizes the intermediate state between microtubule growth and catastrophe by altering microtubule stability in a nucleotide-dependent manner.

bioRxiv · Dec 3, 2022 · PreprintCell Biology

CLASP2 facilitates dynamic actin filament organization along the microtubule lattice

N. C. Rodgers, E. J. Lawrence, A. V. Sawant, N. Efimova, G. Gonzalez-Vasquez, T. T. Hickman, I. Kaverina, M. Zanic

This study shows CLASP2 crosslinks F-actin to microtubules, promoting actin filament organization along microtubule lattices and affecting cytoskeletal structure.

bioRxiv · Sep 22, 2022Cell Biology

Mitotic Spindle Positioning (MISP) is an actin bundler that selectively stabilizes the rootlets of epithelial microvilli

E. A. Morales, C. Arnaiz, E. S. Krystofiak, M. Zanic, M. J. Tyska

The paper identifies MISP as an actin bundler that stabilizes microvillus rootlets and reveals its interaction with ezrin to maintain bundle structure.

bioRxiv · Aug 2, 2021 · PreprintCell Biology

SSNA1 stabilizes dynamic microtubules and detects microtubule damage

B. Lawrence, C. Arnaiz, G. Arpag, M. Zanic

This study investigates SSNA1's effects on microtubules, finding it stabilizes dynamic microtubules and detects damage.

bioRxiv · Feb 5, 2021Biophysics

XMAP215 promotes microtubule catastrophe by disrupting the growing microtubule end

V. J. Farmer, G. Arpag, S. L. Hall, M. Zanic

The paper shows XMAP215 increases microtubule catastrophe frequency despite increasing GTP-cap size, suggesting growth irregularities affect stability.

bioRxiv · Dec 29, 2020Biophysics

Microtubules regulate pancreatic beta cell heterogeneity via spatiotemporal control of insulin secretion hot spots

K. P. Trogden, H. McKinney, X. Zhu, G. Arpag, T. G. Folland, A. B. Osipovich, M. A. Magnuson, M. Zanic, G. Gu, W. R. Holmes, I. Kaverina

This study shows microtubules regulate beta cell heterogeneity in insulin secretion by controlling secretion hot spots through spatiotemporal dynamics.

bioRxiv · Jun 12, 2020Cell Biology

Quantification of Microtubule Stutters: Dynamic Instability Behaviors that are Strongly Associated with Catastrophe

S. M. Mahserejian, J. P. Scripture, A. J. Mauro, E. J. Lawrence, E. M. Jonasson, K. S. Murray, J. Li, M. K. Gardner, M. Alber, M. Zanic, H. V. Goodson

The paper introduces STADIA, a tool to quantify microtubule dynamics, including stutters, and shows stutters precede catastrophes, with CLASP2{gamma} promoting their return to growth.

bioRxiv · Dec 16, 2019Cell Biology

Structural state recognition facilitates tip tracking of EB1 at growing microtubule ends in cells

T. A. Reid, C. Coombes, S. Mukherjee, R. Goldblum, K. White, S. Parmar, M. McClellan, M. Zanic, N. Courtemanche, M. K. Gardner

The paper shows that EB1 tracks microtubule ends by recognizing structural changes, not just GTP-tubulin binding, using simulations and experiments.

bioRxiv · May 13, 2019Cell Biology

Microtubule minus-end aster organization is driven by processive HSET-tubulin clusters

S. R. Norris, S. Jung, P. Singh, C. E. Strothman, A. L. Erwin, M. D. Ohi, M. Zanic, R. Ohi

This study shows HSET forms MT asters using soluble tubulin, not pre-formed MTs, and proposes a model where tubulin availability governs aster versus bundle formation.

bioRxiv · Mar 8, 2018Biophysics