The bone microenvironment invigorates metastatic seeds for further dissemination
W. Zhang, I. L. Bado, H. Wang, S. Singh, H.-C. Lo, M. Niu, Z. Xu, J. Liu, W. Jiang, Y. Li, J. Hu, X. H. - F. Zhang
This study shows the bone microenvironment enhances metastatic potential of cancer cells, enabling further dissemination and multi-organ metastasis, independent of genetic selection.
bioRxiv · Nov 16, 2020Cancer Biology