Pharmacology & ToxicologybioRxivPreprint
RAG-17: A Novel siRNA Conjugate Demonstrating Efficacy in Late-Stage Treatment of SOD1G93A ALS mice
C. Duan, M. Kang, K. Liu…·L.-C. Li
This study introduces RD-12500, an siRNA conjugate that effectively reduces SOD1 levels and delays disease progression in late-stage SOD1G93A ALS mice.
DOI 10.1101/2023.11.23.568255