Author

I. Sequeira

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Cancer Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Organism:human· 2 Assay:metagenomics· 2 Organism:mouse· 2 Assay:proteomics· 2 Assay:scRNA-seq· 2 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

A. Hasuike· 1 shared A. Lobley· 1 shared A. S. Almeida· 1 shared A. V. Predeus· 1 shared B. F. Matuck· 1 shared B. Flemer· 1 shared B. Fremin· 1 shared B. M. Warner· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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1 shared paperCell Biology

A. Hasuike

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Cell-Vision Fusion: A Swin Transformer-based Approach to Predicting Kinase Inhibitor Mechanism of Action from Cell Painting Data

W. Dee, I. Sequeira, A. Lobley, G. Slabaugh

This paper develops a Swin Transformer-based model to predict kinase inhibitor mechanisms of action from Cell Painting data, achieving higher accuracy than traditional image-based profile methods.

bioRxiv · Dec 13, 2023Cell Biology

Polybacterial intracellular coinfection of epithelial stem cells in periodontitis

Q. T. Easter, B. F. Matuck, G. B. Stark, C. L. Worth, A. V. Predeus, B. Fremin, K. T. Huynh, V. Ranganathan, D. Pereira, T. Weaver, K. Miller, P. Perez, A. Hasuike, Z. Chen, M. Bush, , K. M. Byrd

This study identifies polybacterial intracellular co-infection in human periodontal epithelial cells, revealing its proinflammatory effects and potential role in chronic diseases.

bioRxiv · Aug 23, 2023 · PreprintCell Biology

Fiber-associated Lachnospiraceae reduce colon tumorigenesis by modulation of the tumor-immune microenvironment

A. S. Almeida, T. T. T. Tran, T. S. Ghosh, C. Ribiere, C. Foley, L. A. Alves, P. Pellanda, W. Frei, C. M. Hueston, R. Kumar, B. Flemer, I. Sequeira, M. O'Riordain, F. Shanahan, P. W. O'Toole

The paper shows that Lachnospiraceae-type gut microbiomes reduce colon tumorigenesis by modulating the tumor-immune microenvironment.

bioRxiv · Feb 24, 2021 · PreprintMicrobiology

The molecular anatomy of mouse skin during hair growth and rest

S. Joost, K. Annusver, T. Jacob, X. Sun, U. Sivan, T. Dalessandri, I. Sequeira, R. Sandberg, M. Kasper

The paper creates a comprehensive single-cell transcriptome atlas of mouse skin during hair growth and rest, identifying key cell populations and their molecular and spatial organization.

bioRxiv · Aug 30, 2019Cell Biology

IMMUNOMODULATORY ROLE OF KERATIN 76 IN ORAL AND GASTRIC CANCER

I. Sequeira, J. F. Neves, D. Carrero, Q. Peng, N. Palasz, K. Liakath-Ali, G. Lord, P. R. Morgan, G. Lombardi, F. M. Watt

This study shows that Krt76 loss in epithelial cells promotes carcinogenesis by enhancing Treg function and pro-inflammatory cytokines in mouse models and human OSCC.

bioRxiv · Apr 21, 2018Cancer Biology