Physical and data structure of 3D genome
K. Huang, Y. Li, A. R. Shim…·I. Szleifer
This paper proposes a tree-like data structure for the 3D genome to explain its physical properties and folding principles.
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5 papers
Recent·Most cited
K. Huang, Y. Li, A. R. Shim…·I. Szleifer
This paper proposes a tree-like data structure for the 3D genome to explain its physical properties and folding principles.
K. Huang, M. Tagliazucchi, S. H. Park…·I. Szleifer
The paper develops a molecular model of the nuclear pore complex's central transporter, revealing a thermoreversible FG-network with distinct territories for different FG motifs.
A. A. Icazatti, J. M. Loyola, I. Szleifer…·O. A. Martin
This study uses 13C' chemical shifts and machine learning to classify RNA backbone conformations into rotamers and discusses limitations of theoretical computations.
S. Gladstein, L. M. Almassalha, L. Cherkezyan…·V. Backman
This paper introduces a multimodal interferometric imaging platform to study nanoscale structure and macromolecular dynamics in live cells, revealing a new phenomenon called cellular paroxysm induced by UV light.
X. Zhou, L. Almassalha, Y. Li…·V. Backman
This study evaluates how cytological preparation affects nanoscale chromatin changes using PWS microscopy in cancer cell models, showing that modifications can preserve clinically relevant nanoscopic differences.