BiochemistrybioRxiv
Mammalian stringent-like response mediated by the cytosolic NADPH phosphatase MESH1
C.-K. C. Ding, J. Rose, J. Wu…·J.-T. A. Chi
This study identifies MESH1 as a cytosolic NADPH phosphatase that promotes cell survival under ferroptosis by maintaining NADPH levels and induces transcriptional changes resembling bacterial stringent response.
DOI 10.1038/s42255-020-0181-1