Author

J. Braz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 2 Research Focus:drug response / drug discovery· 2 Organism:mouse· 2 Approach:experimental assay· 1 Assay:proteomics· 1 Assay:structural biology· 1

Frequent Co-Authors

A. Basbaum· 2 shared B. K. Shoichet· 2 shared B. L. Roth· 2 shared A. Manglik· 1 shared A. Seth· 1 shared B. Bekele· 1 shared B. J. Bender· 1 shared C. B. Billesbolle· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersPharmacology & Toxicology

A. Basbaum

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Author profile →

2 papers

Recent·Most cited

Structure-Based Discovery of a NPFF1R Antagonist with Analgesic Activity

B. J. Bender, J. E. Pickett, J. Braz, H. J. Kang, S. Gahbauer, K. Bhardwaj, S. Rodriguez-Rosado, Y. Liu, M. Jain, A. Basbaum, B. L. Roth, B. K. Shoichet

This paper identifies a selective NPFF1R antagonist with analgesic properties, showing enhanced pain relief when combined with morphine and reduced side effects.

bioRxiv · Oct 25, 2023 · PreprintPharmacology & Toxicology

Structure-based Discovery of Conformationally Selective Inhibitors of the Serotonin Transporter

I. Singh, A. Seth, C. B. Billesbolle, J. Braz, R. M. Rodriguiz, K. Roy, B. Bekele, V. Craik, X.-P. Huang, D. Boytsov, P. Lak, H. R. O'Donnell, W. R. Sandtner, B. L. Roth, A. Basbaum, , G. Rudnick

The paper identifies two novel inhibitors of the serotonin transporter that selectively target the inward-open conformation, showing improved potency and reduced off-target effects compared to existing drugs.

bioRxiv · Jun 13, 2022Biochemistry