BiochemistrybioRxivPreprint
Ribosome association primes the stringent factor Rel for recruitment of deacylated tRNA to ribosomal A-site
H. Takada, M. Roghanian, J. Caballero-Montes…·V. Hauryliuk
The paper reveals how RelA/SpoT Homolog factor Rel in Bacillus subtilis detects amino acid starvation by interacting with deacylated tRNA on the ribosome, triggering (p)ppGpp synthesis.
DOI 10.1101/2020.01.17.910273