Author

J. Cross

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Assay:proteomics· 2 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:clustering· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. H. Settle· 1 shared A. M. Yakimov· 1 shared A. Rai· 1 shared A. Sawh· 1 shared A. T. Brunger· 1 shared A.-L. L. Sepp· 1 shared B. Claridge· 1 shared B. Czako· 1 shared

Activity by Year

2022-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperCell Biology

A. H. Settle

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Author profile →

4 papers

Recent·Most cited

Multi-omics discovery of hallmark protein and lipid features of circulating small extracellular vesicles in humans

A. Rai, K. Huynh, Q. H. Poh, H. Fang, B. Claridge, J. Cross, T. Duong, C. Duarte, J. Shaw, T. Marwick, P. Meikle, D. W. Greening

The paper identifies hallmark protein and lipid features of circulating extracellular vesicles in humans using multi-omics analysis and provides an open-source tool for further exploration.

bioRxiv · Mar 16, 2024Cell Biology

Plasma membrane abundance dictates phagocytic capacity and functional crosstalk in myeloid cells

B. Y. Winer, A. H. Settle, A. M. Yakimov, C. Jeronimo, T. Lazarovt, M. Tipping, M. Saoi, A. Sawh, A.-L. L. Sepp, M. Galiano, J. S. A. Perry, Y. Y. Wong, F. Geissmann, J. Cross, T. Zhou, , M. Huse

This study shows that plasma membrane abundance regulates phagocytic capacity and post-phagocytic migration in myeloid cells, with G{beta}4 deficiency leading to increased phagocytosis and altered trafficking.

bioRxiv · Sep 12, 2023 · PreprintCell Biology

Lysosome damage triggers direct ATG8 conjugation and ATG2 engagement via CASM

J. Cross, J. Durgan, D. G. McEwan, O. Florey

The paper identifies a direct ATG8 conjugation response to lysosome damage, distinct from lysophagy, involving ATG2 and lipid transfer.

bioRxiv · Mar 22, 2023 · PreprintCell Biology

Screening of hydrocarbon-stapled peptides for inhibition of calcium-triggered exocytosis

Y. Lai, M. Tuvim, J. Leitz, J. J. Peters, R. Pfuetzner, L. Esquivies, Q. Zhou, B. Czako, J. Cross, P. Jones, B. Dickey, A. T. Brunger

The paper screens hydrocarbon-stapled peptides targeting the SNARE-Syt1 primary interface to inhibit Ca2+-triggered exocytosis and mucus hypersecretion.

bioRxiv · Mar 21, 2022Pharmacology & Toxicology