Author

A. T. Brunger

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1 Microbiology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Approach:microscopy & imaging analysis· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1

Frequent Co-Authors

L. Esquivies· 2 shared A. J. B. Kreutzberger· 1 shared A. Orr· 1 shared B. Czako· 1 shared B. Dickey· 1 shared C. A. Doyle· 1 shared C. Wang· 1 shared G. Balistreri· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersMicrobiology

L. Esquivies

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Author profile →

4 papers

Recent·Most cited

MicrobiologybioRxivAug 11, 2022

Nanomolar inhibition of SARS-CoV-2 infection by an unmodified peptide targeting the pre-hairpin intermediate of the spike protein

K. Yang, C. Wang, A. J. B. Kreutzberger…·A. T. Brunger

DOI 10.1073/pnas.2210990119

experimental assayhost-pathogen & immune response

𝕏 PostBluesky

Pharmacology & ToxicologybioRxivMar 21, 2022

Screening of hydrocarbon-stapled peptides for inhibition of calcium-triggered exocytosis

Y. Lai, M. Tuvim, J. Leitz…·A. T. Brunger

The paper screens hydrocarbon-stapled peptides targeting the SNARE-Syt1 primary interface to inhibit Ca2+-triggered exocytosis and mucus hypersecretion.

DOI 10.3389/fphar.2022.891041

experimental assaydrug response / drug discovery

𝕏 PostBluesky

BiochemistrybioRxivFeb 16, 2021

Sec17/Sec18 can support membrane fusion without help from completion of SNARE zippering

H. Song, T. L. Torng, A. Orr…·W. T. Wickner

The paper shows Sec17/Sec18 can drive membrane fusion independently of SNARE zippering completion.

DOI 10.7554/elife.67578

experimental assay

𝕏 PostBluesky

BiophysicsbioRxivDec 17, 2020

Conformational dynamics of auto-inhibition in the ER calcium sensor STIM1

S. van Dorp, R. Qiu, U. B. Choi…·R. S. Lewis

This study investigates the structural dynamics of STIM1's auto-inhibition mechanism using smFRET and crosslinking, revealing how CC1 interacts with CAD to regulate SOCE.

DOI 10.7554/elife.66194

protein structureexperimental assay

𝕏 PostBluesky