Plasma membrane abundance dictates phagocytic capacity and functional crosstalk in myeloid cells
B. Y. Winer, A. H. Settle, A. M. Yakimov, C. Jeronimo, T. Lazarovt, M. Tipping, M. Saoi, A. Sawh, A.-L. L. Sepp, M. Galiano, J. S. A. Perry, Y. Y. Wong, F. Geissmann, J. Cross, T. Zhou, , M. Huse
This study shows that plasma membrane abundance regulates phagocytic capacity and post-phagocytic migration in myeloid cells, with G{beta}4 deficiency leading to increased phagocytosis and altered trafficking.
bioRxiv · Sep 12, 2023 · PreprintCell Biology