Author

J. Dick

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 4 Ecology· 1

Signature Assays, Organisms & Methods

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Research Focus:gene regulatory network inference· 4 Organism:human· 4 Research Focus:differential expression· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:clustering· 2 Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

A. Arruda· 2 shared A. Mitchell· 2 shared A. Murison· 2 shared C. Arlidge· 2 shared H. Boutzen· 2 shared M. Lupien· 2 shared M. Minden· 2 shared A. Ang Houle· 1 shared

Activity by Year

2021-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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2 shared papersCancer Biology

A. Arruda

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

HIF-1 activated by PIM1 assembles a pathological transcription complex and regulon that drives JAK2V617F MPN disease

D. Kealy, R. Ellerington, S. Bansal, A. G. X. Zeng, J. J. F. Medeiros, K. A. West, N.-M. Blacknell, C. A. Hawley, J. Lukaszonek, R. Gawne, H. M. Khoo, G. Caalim, B. Drylie, J. Chatzigerou, B. Rodriguez Lima Ferreira, , K. S. Bridge

This study identifies that HIF-1 activation by PIM1 in JAK2V617F-MPNs drives non-canonical transcription complex formation and disease progression.

bioRxiv · Jul 2, 2024 · PreprintCancer Biology

A primary patient-derived model for investigating functional heterogeneity within the human Leukemic Stem Cell Compartment

H. Boutzen, M. Chan-Seng-Yue, A. Murison, N. Mbong, E. Wagenblast, C. Arlidge, S. A. Madani Tonekaboni, E. Orouji, A. Arruda, A. Mitchell, F. Notta, M. Lupien, M. Minden, K. Kaufmann, J. Dick

bioRxiv · Mar 1, 2022 · PreprintCancer Biology

Interacting evolutionary pressures drive mutation dynamics and health outcomes in aging blood

K. Skead, A. Ang Houle, S. Abelson, M. Agbessi, V. Bruat, B. Lin, D. Soave, L. Shlush, S. Wright, J. Dick, Q. Morris, P. Awadalla

The paper models positive and negative selection in blood cells to explain why some people with ARCH do not progress to AML, finding that passenger mutation burden influences clonal dominance.

Nature Communications · Aug 13, 2021Peer-reviewedCancer Biology

Mangrove forests mitigate coral bleaching under thermal stress from climate change

J. Johnson, J. Dick, D. Pincheira-Donoso

This study shows that coral reefs near mangroves are more resistant to bleaching under thermal stress than those without mangrove association.

bioRxiv · Jun 4, 2021 · PreprintEcology

Transposable Elements Shape Stemness in Normal and Leukemic Hematopoiesis

G. Grillo, B. Nadorp, A. Qamra, A. Mitchell, C. Arlidge, A. Nand, N. Takayama, A. Murison, S. A. M. Tonekaboni, A. Arruda, J. Wang, M. Minden, O. Deniz, H. Boutzen, J. Dick, M. Lupien

The paper identifies transposable elements (TEs) as genetic drivers of stemness in normal and leukemic hematopoiesis, showing their role in maintaining stem cell properties through chromatin accessibility.

bioRxiv · Feb 16, 2021Cancer Biology