J. E. Galan

The paper reports the cryo-EM structure of SipA bound to F-actin, revealing how it stabilizes actin filaments and shows this activity is separate from its role in inflammation.

This study maps the assembly of the type III secretion sorting platform using structure modeling and in vivo crosslinking, revealing inter-subunit interactions and the genetic basis of its formation.

This study identifies the cellular machinery and receptor involved in the exocytic transport of typhoid toxin from Salmonella Typhi-infected cells.

This study shows that Salmonella Typhi produces two distinct typhoid toxin variants with different delivery components but shared active subunits, leading to functional versatility.

This study uses cryo-electron tomography to visualize the Salmonella-host cell interface mediated by the type III secretion system, revealing the translocon's structure and its role in effector translocation.