Author

E. Guo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Microbiology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:proteomics· 2 Organism:bacteria (other)· 1 Research Focus:cell type annotation· 1 Organism:chicken / avian· 1 Assay:cryo-EM· 1

Frequent Co-Authors

B. T. Kuhn· 1 shared C. Sun· 1 shared C. Yu· 1 shared G. B. Rehm· 1 shared H. Guo· 1 shared I. Cortes-Puch· 1 shared J. E. Galan· 1 shared J. Jia· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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1 shared paperPhysiology

B. T. Kuhn

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Cryo-EM structure of the bacterial effector protein SipA bound to F-actin reveals a unique mechanism for filament stabilization

E. Guo, S. Z. Chou, M. Lara-Tejero, J. E. Galan

The paper reports the cryo-EM structure of SipA bound to F-actin, revealing how it stabilizes actin filaments and shows this activity is separate from its role in inflammation.

bioRxiv · Dec 21, 2023 · PreprintMicrobiology

Preclinical Basis of the Efficacy and Pharmacodynamics of Finotonlimab, a Humanized Anti-PD-1 Monoclonal Antibody with Potent Implications for Clinical Benefit

X. Yang, J. Li, E. Guo, C. Sun, X. Zhang, J. Jia, R. Wang, J. Ma, Y. Dai, M. Deng, C. Yu, L. Sun, S. Li, L. Xie

This paper evaluates the preclinical efficacy and pharmacodynamics of Finotonlimab, a humanized anti-PD-1 antibody, showing high PD-1 binding affinity and sustained receptor occupancy in cynomolgus monkeys.

bioRxiv · Jan 16, 2023 · PreprintImmunology

CD8 T cell epitope generation toward the continually mutating SARS-CoV-2 spike protein in genetically diverse human population: Implications for disease control and prevention

H. Guo, E. Guo

The paper identifies CD8 T cell epitopes for SARS-CoV-2 spike protein across diverse HLA alleles and finds mutations affecting epitope presentation, linking HLA diversity to infection risk.

bioRxiv · Sep 10, 2020Immunology

An Analytic Platform for the Rapid and Reproducible Annotation of Ventilator Waveform Data

G. B. Rehm, B. T. Kuhn, M. K. Lieng, I. Cortes-Puch, J. Nguyen, E. Guo, J.-P. Delplanque, N. R. Anderson, J. Y. Adams

The paper introduces APL, a system for annotating ventilator waveform data with features for multi-reviewer adjudication and gold standard dataset creation.

bioRxiv · Mar 6, 2019 · PreprintPhysiology