Author

J. Fodor

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Immunology· 2 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Approach:mechanistic / dynamical model· 2 Research Focus:protein folding & dynamics· 2 Assay:structural biology· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

A. M. Buckle· 4 shared B. T. Riley· 3 shared B. T. Porebski· 2 shared D. E. Hoke· 2 shared I. Kass· 2 shared M. G. Costa· 2 shared N. A. Borg· 2 shared S. McGowan· 2 shared

Activity by Year

2018-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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4 shared papersBiochemistry

A. M. Buckle

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Structure and dynamics of the autoantigen GAD65 in complex with the human autoimmune polyendocrine syndrome type 2-associated autoantibody b96.11

S. Stander, C. F. Reboul, S. N. Lee, D. Williams, P. G. Chandler, M. G. Costa, D. E. Hoke, J. D. Jimma, J. Fodor, G. Fenalti, S. I. Mannering, B. T. Porebski, P. Schofield, D. Christ, M. Buckle, , A. M. Buckle

This study characterizes the structure and dynamics of GAD65 and its interaction with autoantibody b96.11, revealing how intrinsic conformational flexibility drives autoantigenicity.

bioRxiv · Mar 18, 2024 · PreprintBiochemistry

Septin-7 is indispensable for proper skeletal muscle architecture and function

M. Gonczi, Z. Raduly, L. Szabo, J. Fodor, A. Telek, N. Dobrosi, N. Balogh, P. Szentesi, G. Kis, M. Antal, G. Trencsenyi, B. Dienes, L. Csernoch

This study shows Septin-7 is essential for skeletal muscle structure and function, as its absence causes deformities, reduced force generation, and impaired myotube differentiation.

bioRxiv · Nov 24, 2021 · PreprintPhysiology

The Role of Conformational Dynamics in Abacavir-Induced Hypersensitivity Syndrome

J. Fodor, B. T. Riley, I. Kass, A. M. Buckle, N. A. Borg

This study uses molecular dynamics to show abacavir alters peptide conformations bound to HLA-B*57:01, influencing immune self-reactivity and hypersensitivity.

bioRxiv · Feb 27, 2019Immunology

Reactive Centre Loop Dynamics and Serpin Specificity

E. M. Marijanovic, J. Fodor, B. T. Riley, B. T. Porebski, M. G. Costa, I. Kass, D. E. Hoke, S. McGowan, A. M. Buckle

This study investigates serpin specificity by engineering the reactive centre loop (RCL) of a synthetic serpin, finding that RCL sequence alone does not determine specificity, and that local electrostatics and dynamics also play critical roles.

bioRxiv · Aug 14, 2018Biochemistry

Previously Hidden Dynamics at the TCR-pMHC Interface Revealed

J. Fodor, B. T. Riley, N. A. Borg, A. M. Buckle

The paper reveals hidden conformational dynamics in TCR-pMHC interactions using ensemble refinement of X-ray crystallographic data, enhancing functional interpretations of immune responses.

bioRxiv · Feb 21, 2018Immunology