Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
4 papers
Recent·Most cited
P. G. Chandler, L. L. Tan, B. T. Porebski…·A. M. Buckle
This paper grafts binding loops from an Adnectin onto a pre-stabilized FN3Con scaffold to create a stable monobody that binds VEGFR2 with high affinity and long-term stability.
N. W. Zammit, O. M. Siggs, P. Gray…·M. E. Craig
The paper identifies TNFAIP3 variants in humans, Denisovans, and mice that modulate A20 phosphorylation, revealing a genetic mechanism for balancing immunity and microbial tolerance.
E. M. Marijanovic, J. Fodor, B. T. Riley…·A. M. Buckle
This study investigates serpin specificity by engineering the reactive centre loop (RCL) of a synthetic serpin, finding that RCL sequence alone does not determine specificity, and that local electrostatics and dynamics also play critical roles.
C. Li, L. V. Clark, R. Zhang…·A. M. Buckle
The paper identifies structural capacitance as a new mechanism in protein evolution that generates microstructure in disordered regions, linking it to disease and evolutionary adaptability.