Netrin-1 binding to Unc5B regulates Blood-Retina Barrier integrity
J. Furtado, L. H. Geraldo, F. S. Leser…·K. Boye
This study shows Netrin-1 binding to Unc5B regulates blood-retina barrier integrity through Norrin/{beta}-catenin signaling.
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3 papers
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J. Furtado, L. H. Geraldo, F. S. Leser…·K. Boye
This study shows Netrin-1 binding to Unc5B regulates blood-retina barrier integrity through Norrin/{beta}-catenin signaling.
K. Boye, L. H. M. Geraldo, J. furtado…·A. Eichmann
This study shows that endothelial Unc5B maintains blood-brain barrier integrity via Wnt/{beta}-catenin signaling, with potential therapeutic applications for CNS diseases.
H. Park, J. Furtado, M. Poulet…·A. Eichmann
This study shows that defective flow-migration coupling due to ALK1 loss causes arteriovenous malformations in HHT, with integrin-YAP/TAZ signaling as a potential therapeutic target.