RORγt+ B cells express proinflammatory cytokines and promote allo- and auto- immunity
Q. Ding, Y. Wu, A. Zuchowski, E. T. Triglia, J. Gommerman, A. Subramanian, V. K. Kuchroo, D. M. Rothstein
The paper identifies TIM-4+ B cells that express proinflammatory cytokines like IL-17A and promote auto- and allo-immunity by preventing their conversion into regulatory B cells.
bioRxiv · Sep 22, 2023 · PreprintImmunology