Author

J. Hadfield

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 4 Microbiology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 6 Research Focus:host-pathogen & immune response· 4 Assay:whole-genome sequencing· 4 Organism:virus· 3 Assay:DNA methylation· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

A. Buser· 2 shared A. Egli· 2 shared A. Zeller· 2 shared C. Saalfrank· 2 shared D. Lang· 2 shared H. M. Seth-Smith· 2 shared M. Battegay· 2 shared M. Brunner· 2 shared

Activity by Year

2017-2020 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersEvolutionary Biology

A. Buser

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

A phylodynamic workflow to rapidly gain insights into the dispersal history and dynamics of SARS-CoV-2 lineages

S. Dellicour, K. Durkin, S. L. Hong, B. Vanmechelen, J. Marti-Carreras, M. S. Gill, C. Meex, S. Bontems, E. Andre, M. Gilbert, C. Walker, N. De Maio, N. R. Faria, J. Hadfield, M.-P. Hayette, , P. Maes

This paper introduces a phylodynamic workflow to analyze SARS-CoV-2 lineage dispersal, showing external introductions were key in Belgium and lockdowns had limited impact on transmission.

bioRxiv · May 5, 2020Evolutionary Biology

Characterising the epidemic spread of Influenza A/H3N2 within a city through phylogenetics

N. F. Müller, D. Wüthrich, N. Goldman, N. Sailer, C. Saalfrank, M. Brunner, N. Augustin, H. M. Seth-Smith, Y. Hollenstein, M. Syedbasha, D. Lang, R. A. Neher, O. Dubuis, M. Naegele, A. Buser, , T. Stadler

The paper uses genetic sequence data and patient metadata to analyze local influenza transmission dynamics in Basel, Switzerland, finding that temperature trends correlate with transmission and that elderly and school children drive different transmission networks.

bioRxiv · Apr 27, 2020Evolutionary Biology

High-resolution influenza mapping of a city reveals socioeconomic determinants of transmission within and between urban quarters

A. Egli, N. Goldman, N. F. Müller, M. Brunner, D. Wuethrich, S. Tschudin-Sutter, E. Hodcroft, R. Neher, C. Saalfrank, J. Hadfield, T. Bedfors, M. Syedbasha, T. Vogel, N. Augustin, J. Bauer, , R. Schneider-Sliwa

This study maps influenza transmission in a city at high resolution, finding socioeconomic factors like income influence infection patterns and vaccination rates, independent of population density.

bioRxiv · Apr 3, 2020 · PreprintMicrobiology

An emergent clade of SARS-CoV-2 linked to returned travellers from Iran

J.-S. Eden, R. Rockett, I. Carter, H. Rahman, J. de Ligt, J. Hadfield, M. Storey, X. Ren, R. Tulloch, K. Basile, J. Wells, R. Byun, N. Gliroy, M. V. O'Sullivan, V. Sintchenko, , J. Kok

The paper identifies a distinct SARS-CoV-2 clade linked to travellers returning from Iran to Australia and New Zealand through whole genome sequencing and phylogenetic analysis.

bioRxiv · Mar 15, 2020Microbiology

Independence of HIF1a and androgen signaling pathways in prostate cancer

M. G. Tran, B. A. Bibby, L. Yang, F. Lo, A. Warren, D. Shukla, M. Osborne, J. Hadfield, T. Carroll, R. Stark, H. Scott, A. Ramos-Montoya, C. Massie, P. Maxwell, C. M. West, , D. Neal

The paper investigates the relationship between HIF1a and androgen signaling pathways in prostate cancer, finding they operate independently and identify shared genes associated with poor prognosis.

bioRxiv · Nov 26, 2019Cancer Biology

RNA interference pathways display high rates of adaptive protein evolution across multiple invertebrates

W. H. Palmer, J. Hadfield, D. J. Obbard

The paper examines adaptive protein evolution in RNAi pathway genes across eight invertebrates, finding higher rates of adaptive substitution in these genes compared to others.

Genetics · Apr 1, 2018Peer-reviewedEvolutionary Biology

Nextstrain: real-time tracking of pathogen evolution

J. Hadfield, C. Megill, S. M. Bell, J. Huddleston, B. Potter, C. Callender, P. Sagulenko, T. Bedford, R. A. Neher

Nextstrain provides real-time tracking of pathogen evolution by integrating viral genome data with other public health data through a database, bioinformatics pipeline, and visualization platform.

bioRxiv · Nov 22, 2017Evolutionary Biology