Author

J. Hegermann

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Bioengineering· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Organism:mouse· 1 Assay:proteomics· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

A. Akbal· 1 shared A. Schroeder· 1 shared B. O. Staar· 1 shared B. Schuster· 1 shared C. Stamme· 1 shared D. Krause· 1 shared D. P. Martin· 1 shared D. Roth· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperImmunology

A. Akbal

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Cytosolic sodium accumulation is a common danger signal triggering endocytic dysfunction and NLRP3 inflammasome activation

M. S. J. Mangan, A. Akbal, S. Rivara, A. Schroeder, G. L. Horvath, P. Walch, J. Hegermann, R. Kaiser, F. Duthie, J. Selkrig, J. Jantsch, R. Gerhard, D. Wachten, E. Latz

The paper shows that cytosolic sodium accumulation triggers NLRP3 inflammasome activation in response to various danger signals in human macrophages.

bioRxiv · Mar 26, 2024 · PreprintImmunology

Primary Ciliary Dyskinesia patient specific hiPSC-derived airway epithelium in Air Liquid Interface culture recapitulates disease specific phenotypes in vitro

L. von Schledorn, D. P. Martin, N. Cleve, J. Zoellner, D. Roth, B. O. Staar, J. Hegermann, F. Ringshausen, J. C. Nawroth, U. Martin, R. Olmer

The paper develops an in vitro model of PCD using hiPSC-derived airway epithelium that recapitulates disease-specific phenotypes.

bioRxiv · Apr 25, 2023 · PreprintBioengineering

LAMP3 is critical for surfactant homeostasis in mice

L. P. Lunding, D. Krause, G. Stichtenoth, C. Stamme, N. Lauterbach, J. Hegermann, M. Ochs, B. Schuster, R. Sedlacek, P. Saftig, D. Schwudke, M. Wegmann, M. Damme

This study shows that LAMP3 is essential for maintaining pulmonary surfactant homeostasis in mice, as its absence leads to altered surfactant composition and lung function.

bioRxiv · Feb 5, 2021 · PreprintBiochemistry