Author

B. Schuster

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Bioengineering· 1 Biophysics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:deep learning· 2 Approach:experimental assay· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

S. Tay· 2 shared A. G. Simpkins· 1 shared A. Jaochimiak· 1 shared A. K. Ranganath· 1 shared A. Rzhetsky· 1 shared B. C. Dickinson· 1 shared B. C. Mounce· 1 shared C. B. Brooke· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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2 shared papersBioengineering

S. Tay

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

OrganoID: a versatile deep learning platform for tracking and analysis of single-organoid dynamics

J. M. Matthews, B. Schuster, S. S. Kashaf, P. Liu, R. Ben-Yishay, D. Ishay-Ronen, L. Shen, C. Weber, M. Bielski, S. S. Kupfer, M. Bilgic, A. Rzhetsky, S. Tay

OrganoID automatically tracks and analyzes single-organoid dynamics in microscopy images, showing high accuracy in counting, sizing, and morphology analysis across multiple organoid types.

bioRxiv · Jan 13, 2022Bioengineering

LAMP3 is critical for surfactant homeostasis in mice

L. P. Lunding, D. Krause, G. Stichtenoth, C. Stamme, N. Lauterbach, J. Hegermann, M. Ochs, B. Schuster, R. Sedlacek, P. Saftig, D. Schwudke, M. Wegmann, M. Damme

This study shows that LAMP3 is essential for maintaining pulmonary surfactant homeostasis in mice, as its absence leads to altered surfactant composition and lung function.

bioRxiv · Feb 5, 2021 · PreprintBiochemistry

Drug repurposing screen identifies masitinib as a 3CLpro inhibitor that blocks replication of SARS-CoV-2 in vitro

N. Drayman, K. A. Jones, S.-A. Azizi, H. M. Froggatt, K. Tan, N. Ivanova Maltseva, S. Chen, V. Nicolaescu, S. Dvorkin, K. Furlong, R. S. Kathayat, M. R. Firpo, V. Mastrodomenico, E. A. Bruce, M. M. Schmidt, , S. Tay

The paper screens 1,900 drugs to find inhibitors of SARS-CoV-2 replication, identifies masitinib as a 3CLpro inhibitor effective in vitro, and shows its broad anti-viral activity.

bioRxiv · Aug 31, 2020Microbiology

Identifying Sequence Perturbations to an Intrinsically Disordered Protein that Determine Its Phase Separation Behavior

B. Schuster, G. L. Dignon, W. S. Tang, F. Kelley, A. K. Ranganath, C. N. Jahnke, A. G. Simpkins, R. M. Regy, D. A. Hammer, M. C. Good, J. Mittal

This study identifies sequence features of an intrinsically disordered protein that influence its phase separation behavior through computational modeling and experimental validation.

bioRxiv · Jan 6, 2020Biophysics