Author

J. J. Pfannenstiel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Fehr· 2 shared A. Galera-Prat· 1 shared C. A. Miller· 1 shared C. M. Kerr· 1 shared D. Chanda· 1 shared D. Cluff· 1 shared D. V. Ferraris· 1 shared J. J. O'Connor· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBiochemistry

A. Fehr

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2 papers

Recent·Most cited

BiochemistrybioRxivPreprintAug 28, 2023

Discovery of 2-amide-3-methylester thiophenes that target SARS-CoV-2 Mac1 and repress coronavirus replication, validating Mac1 as an anti-viral target

S. Wazir, T. A. O. Parviainen, M. M. Maksimainen…·L. Lehtiö

This paper identifies small molecule inhibitors of SARS-CoV-2 Mac1 that inhibit coronavirus replication, validating Mac1 as an anti-viral target.

DOI 10.1101/2023.08.28.555062

experimental assaydrug response / drug discovery

𝕏 PostBluesky

MicrobiologybioRxivPreprintApr 6, 2023

SARS-CoV-2 Mac1 is required for IFN antagonism and efficient virus replication in mice

Y. M. Alhammad, S. Parthasarathy, R. Ghimire…·A. Fehr

This study shows that SARS-CoV-2 Mac1 is essential for pathogenesis but not replication, as Mac1-deleted virus replicates normally but induces higher IFN responses and reduced disease in mice.

DOI 10.1101/2023.04.06.535927

mouseproteomics

𝕏 PostBluesky