Author

A. Pu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:metabolomics· 1

Frequent Co-Authors

J. L. Gommerman· 2 shared L. C. Osborne· 2 shared M. Zuo· 2 shared N. Fettig· 2 shared V. Ramaglia· 2 shared A. Jamaiyar· 1 shared A. Polyzois· 1 shared A. Sharma· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersImmunology

J. L. Gommerman

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Author profile →

3 papers

Recent·Most cited

Mining for disease-associated microbial metabolites in an age-dependent model of multiple sclerosis

A. Pu, N. Fettig, A. Polyzois, G. Chao, I. Naouar, L. Hohman, M. A. Fontaine, M. Zuo, K. Champagne-Jorgensen, J. Copeland, D. Chan, K. M. Davis, R. Yu, S. Popple, N. A. Carranza Garcia, , L. C. Osborne

The paper identifies a microbial metabolite, indole 3-propionic acid, that can reverse non-remitting EAE in aged mice, suggesting therapeutic potential for progressive MS.

bioRxiv · May 27, 2024 · PreprintImmunology

Age related susceptibility to grey matter demyelination and neurodegeneration is associated with meningeal neutrophil accumulation in an animal model of Multiple Sclerosis

M. Zuo, N. Fettig, L.-P. Bernier, E. Possnecker, S. Spring, A. Pu, X. I. Ma, D. S. Lee, L. Ward, A. Sharma, J. Kuhle, J. G. Sled, A.-K. Probstel, B. A. MacVicar, L. C. Osborne, , V. Ramaglia

The paper shows that age-related grey matter demyelination and neurodegeneration in MS are linked to meningeal neutrophil accumulation in an animal model.

bioRxiv · Dec 23, 2021 · PreprintImmunology

Mechanism of the Switch from NO to H2O2 in Endothelium-Dependent Vasodilation in Diabetes

C. Juguilon, Z. Wang, Y. Wang, A. Jamaiyar, M. Enrick, J. Gadd, C.-L. W. Chen, A. Pu, C. Kolz, V. Ohanyan, Y.-R. Chen, Y. Zhang, W. W. Chilian, L. Yin

This study identifies an NO-to-H2O2 switch in diabetic coronary vasodilation mediated by miR-21, contributing to microvascular dysfunction.

bioRxiv · May 18, 2021Physiology