Author

J. Lazar

University of Ljubljana

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Biophysics· 1 Microbiology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:fluorescence / live-cell microscopy· 2 Organism:human· 2 Organism:bacteria (other)· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

P. Dedecker· 2 shared P. S. Miclea· 2 shared R. Van den Eynde· 2 shared W. Vandenberg· 2 shared A. A. Adimora· 1 shared A. Bondar· 1 shared A. Dalal· 1 shared A. K. SHUKLA· 1 shared

Activity by Year

2023-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersPhysiology

P. Dedecker

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Chemical inactivation of a bacterial immune system de-domesticates a temperate phage and promotes its spread

Yanyao Cai, J. LAZAR, Yun Shi, Biswa P. Mishra, Thomas Ve, Anna Dragoš, Joseph P. Gerdt

The paper identifies chemical inhibitors of SpbK, an antiphage defense system in Bacillus subtilis, showing they promote phage dissemination and reveal mechanisms of inhibiting TIR-domain enzymes.

bioRxiv · May 15, 2026 · PreprintBiochemistry

Novel Genetically Encoded Probes for Functional Imaging of Cell Signaling by Polarization Microscopy

P. S. Miclea, V. Nagy Markova, R. Van den Eynde, W. Vandenberg, A. Sakhi, A. Bondar, J. Myskova, P. Dedecker, J. Lazar

This paper introduces FLIPs, a new class of genetically encoded biosensors that enable real-time single-cell imaging of cell signaling without modifying target proteins.

bioRxiv · Feb 23, 2024 · PreprintPhysiology

A genetically-encoded nanobody sensor reveals conformational diversity in beta-arrestins orchestrated by distinct seven transmembrane receptors

P. Sarma, V. N. Markov, N. Zaidi, A. Dalal, S. Mishra, M. K. Yadav, G. Mahajan, N. Roy, P. Miclea, J. Lazar, A. K. SHUKLA

This study introduces a nanobody sensor to detect conformational changes in beta-arrestins upon GPCR activation, revealing receptor-specific conformational diversity.

bioRxiv · Feb 21, 2024Biochemistry

Plasma Glycomic Markers of Accelerated Biological Aging During Chronic HIV Infection

L. B. Giron, Q. Liu, O. S. Adeniji, X. Yin, T. Kannan, J. Ding, D. Y. Lu, S. Langan, J. Zhang, J. L. L. C. Azevedo, S. H. Li, S. Shalygin, P. Azadi, D. B. Hanna, I. Ofotokun, , M. A. Mohsen

This study identifies glycomic alterations in HIV-positive individuals that correlate with accelerated aging and comorbidities, suggesting potential biomarkers for early detection.

bioRxiv · Aug 9, 2023 · PreprintMicrobiology

The TriScan: fast and sensitive 3D confocal fluorescence imaging using a simple optical design

R. Van den Eynde, J. Verheyen, P. S. Miclea, J. Lazar, W. Vandenberg, P. Dedecker

The paper introduces a fast and sensitive 3D confocal fluorescence microscope called TriScan, combining speed and resolution for various applications.

bioRxiv · Apr 11, 2023 · PreprintBiophysics